BDBM260000 US9512132, 36

SMILES: COC[C@H]1CCCN1c1nc(nc2n(Cc3nonc3C)ncc12)C(C)(C)C

InChI Key: InChIKey=QTBLIHDYOKHNQH-CYBMUJFWSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 260000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM260000 (US9512132, 36) Show SMILES COC[C@H]1CCCN1c1nc(nc2n(Cc3nonc3C)ncc12)C(C)(C)C |r| Show InChI InChI=1S/C19H27N7O2/c1-12-15(24-28-23-12)10-26-17-14(9-20-26)16(21-18(22-17)19(2,3)4)25-8-6-7-13(25)11-27-5/h9,13H,6-8,10-11H2,1-5H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X39
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM260000 (US9512132, 36) Show SMILES COC[C@H]1CCCN1c1nc(nc2n(Cc3nonc3C)ncc12)C(C)(C)C |r| Show InChI InChI=1S/C19H27N7O2/c1-12-15(24-28-23-12)10-26-17-14(9-20-26)16(21-18(22-17)19(2,3)4)25-8-6-7-13(25)11-27-5/h9,13H,6-8,10-11H2,1-5H3/t13-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50,000 cells per well in a black 96 well plate with fl...				US Patent US9694012 (2017) BindingDB Entry DOI: 10.7270/Q2VX0DPM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM260000 (US9512132, 36) Show SMILES COC[C@H]1CCCN1c1nc(nc2n(Cc3nonc3C)ncc12)C(C)(C)C |r| Show InChI InChI=1S/C19H27N7O2/c1-12-15(24-28-23-12)10-26-17-14(9-20-26)16(21-18(22-17)19(2,3)4)25-8-6-7-13(25)11-27-5/h9,13H,6-8,10-11H2,1-5H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50,000 cells per well in a black 96 well plate with fl...				US Patent US9694012 (2017) BindingDB Entry DOI: 10.7270/Q2VX0DPM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM260000 (US9512132, 36) Show SMILES COC[C@H]1CCCN1c1nc(nc2n(Cc3nonc3C)ncc12)C(C)(C)C |r| Show InChI InChI=1S/C19H27N7O2/c1-12-15(24-28-23-12)10-26-17-14(9-20-26)16(21-18(22-17)19(2,3)4)25-8-6-7-13(25)11-27-5/h9,13H,6-8,10-11H2,1-5H3/t13-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X39
					More data for this Ligand-Target Pair