BDBM260058 US9522886, 6

SMILES: CNC(=O)CC(C)(C)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1

InChI Key: InChIKey=LPIOARKUUNUKMT-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM260058 (US9522886, 6) Show SMILES CNC(=O)CC(C)(C)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 Show InChI InChI=1S/C19H26F2N4O3/c1-18(2,8-15(26)22-3)24-16(27)13-6-7-14(25-10-19(20,21)11-25)17(23-13)28-9-12-4-5-12/h6-7,12H,4-5,8-11H2,1-3H3,(H,22,26)(H,24,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9522886 (2016) BindingDB Entry DOI: 10.7270/Q28W3C7W
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM260058 (US9522886, 6) Show SMILES CNC(=O)CC(C)(C)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 Show InChI InChI=1S/C19H26F2N4O3/c1-18(2,8-15(26)22-3)24-16(27)13-6-7-14(25-10-19(20,21)11-25)17(23-13)28-9-12-4-5-12/h6-7,12H,4-5,8-11H2,1-3H3,(H,22,26)(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	172	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9522886 (2016) BindingDB Entry DOI: 10.7270/Q28W3C7W
					More data for this Ligand-Target Pair