BDBM260060 US9522886, 8

SMILES: CNC(=O)CC(CCc1ccccc1)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1

InChI Key: InChIKey=KTUOGFSNWGPPCZ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM260060 (US9522886, 8) Show SMILES CNC(=O)CC(CCc1ccccc1)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 Show InChI InChI=1S/C25H30F2N4O3/c1-28-22(32)13-19(10-9-17-5-3-2-4-6-17)29-23(33)20-11-12-21(31-15-25(26,27)16-31)24(30-20)34-14-18-7-8-18/h2-6,11-12,18-19H,7-10,13-16H2,1H3,(H,28,32)(H,29,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9522886 (2016) BindingDB Entry DOI: 10.7270/Q28W3C7W
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM260060 (US9522886, 8) Show SMILES CNC(=O)CC(CCc1ccccc1)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 Show InChI InChI=1S/C25H30F2N4O3/c1-28-22(32)13-19(10-9-17-5-3-2-4-6-17)29-23(33)20-11-12-21(31-15-25(26,27)16-31)24(30-20)34-14-18-7-8-18/h2-6,11-12,18-19H,7-10,13-16H2,1H3,(H,28,32)(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	301	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9522886 (2016) BindingDB Entry DOI: 10.7270/Q28W3C7W
					More data for this Ligand-Target Pair