BDBM2602 (Arylindolyl)maleimide deriv. 24::3-(1-Methyl-3-indolyl)-4-(3-pyrrolyl)-pyrrole-2,5-dione::3-(1-methyl-1H-indol-3-yl)-4-(1H-pyrrol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cc[nH]c2)c2ccccc12

InChI Key: InChIKey=MFGMCPNDXYDUME-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 9 PDB IDs contain this monomer as substructures. 9 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Kinase C (Rattus norvegicus (rat))	BDBM2602 ((Arylindolyl)maleimide deriv. 24 | 3-(1-Methyl-3-i...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cc[nH]c2)c2ccccc12 |t:4| Show InChI InChI=1S/C17H13N3O2/c1-20-9-12(11-4-2-3-5-13(11)20)15-14(10-6-7-18-8-10)16(21)19-17(15)22/h2-9,18H,1H3,(H,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair