BDBM26060 4-methyl-2-[(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]-1,3-thiazole-5-carboxylic acid::BI-83C8

SMILES: Cc1nc(Sc2nnnn2-c2ccccc2)sc1C(O)=O

InChI Key: InChIKey=OKSOZDWPGNSYGR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM26060 (4-methyl-2-[(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)sul...) Show SMILES Cc1nc(Sc2nnnn2-c2ccccc2)sc1C(O)=O Show InChI InChI=1S/C12H9N5O2S2/c1-7-9(10(18)19)20-12(13-7)21-11-14-15-16-17(11)8-5-3-2-4-6-8/h2-6H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	22
Burnham Institute for Medical Research					Assay Description Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...				Proc Natl Acad Sci U S A 105: 16809-13 (2008) Article DOI: 10.1073/pnas.0805677105 BindingDB Entry DOI: 10.7270/Q22N50K9
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM26060 (4-methyl-2-[(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)sul...) Show SMILES Cc1nc(Sc2nnnn2-c2ccccc2)sc1C(O)=O Show InChI InChI=1S/C12H9N5O2S2/c1-7-9(10(18)19)20-12(13-7)21-11-14-15-16-17(11)8-5-3-2-4-6-8/h2-6H,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	7.8	0
Burnham Institute for Medical Research					Assay Description Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...				Proc Natl Acad Sci U S A 105: 16809-13 (2008) Article DOI: 10.1073/pnas.0805677105 BindingDB Entry DOI: 10.7270/Q22N50K9
					More data for this Ligand-Target Pair