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SMILES: N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc3n(CCc4ccccc4)ccc23)n1

InChI Key: InChIKey=YWMUNMBVCJLJJE-JTHBVZDNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260729   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM260729
PNG
(US9533989, 39)
Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc3n(CCc4ccccc4)ccc23)n1
Show InChI InChI=1S/C27H31N7O/c28-21-9-4-5-10-23(21)32-27-30-17-20(25(29)35)26(33-27)31-22-11-6-12-24-19(22)14-16-34(24)15-13-18-7-2-1-3-8-18/h1-3,6-8,11-12,14,16-17,21,23H,4-5,9-10,13,15,28H2,(H2,29,35)(H2,30,31,32,33)/t21-,23+/m0/s1
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US Patent
n/an/a 15.1n/an/an/an/an/an/a



Ziarco Pharma Ltd.

US Patent


Assay Description
The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...

US Patent US9533989 (2017)


BindingDB Entry DOI: 10.7270/Q2VQ31M7
More data for this
Ligand-Target Pair