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SMILES: N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2ccc3CCN(Cc3c2)C(=O)c2ccccc2)n1

InChI Key: InChIKey=ANVUTVJSJJWDEA-XZOQPEGZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260737   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM260737
PNG
(US9533989, 47)
Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2ccc3CCN(Cc3c2)C(=O)c2ccccc2)n1
Show InChI InChI=1S/C27H31N7O2/c28-22-8-4-5-9-23(22)32-27-30-15-21(24(29)35)25(33-27)31-20-11-10-17-12-13-34(16-19(17)14-20)26(36)18-6-2-1-3-7-18/h1-3,6-7,10-11,14-15,22-23H,4-5,8-9,12-13,16,28H2,(H2,29,35)(H2,30,31,32,33)/t22-,23+/m0/s1
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PC cid
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US Patent
n/an/a 17.6n/an/an/an/an/an/a



Ziarco Pharma Ltd.

US Patent


Assay Description
The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...

US Patent US9533989 (2017)


BindingDB Entry DOI: 10.7270/Q2VQ31M7
More data for this
Ligand-Target Pair