BDBM260743 US9533989, 54

SMILES: N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc3n(Cc4ccccc4O)ccc23)n1

InChI Key: InChIKey=PZWFUEYLLNFBLA-PZJWPPBQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM260743 (US9533989, 54) Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc3n(Cc4ccccc4O)ccc23)n1 Show InChI InChI=1S/C26H29N7O2/c27-19-7-2-3-8-21(19)31-26-29-14-18(24(28)35)25(32-26)30-20-9-5-10-22-17(20)12-13-33(22)15-16-6-1-4-11-23(16)34/h1,4-6,9-14,19,21,34H,2-3,7-8,15,27H2,(H2,28,35)(H2,29,30,31,32)/t19-,21+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.5	n/a	n/a	n/a	n/a	n/a	n/a
Ziarco Pharma Ltd. US Patent					Assay Description The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...				US Patent US9533989 (2017) BindingDB Entry DOI: 10.7270/Q2VQ31M7
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