BDBM260745 US9533989, 56

SMILES: N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2ccc3CCN(Cc3c2)C(=O)c2cccc(F)c2)n1

InChI Key: InChIKey=XTRVSHAUGBMDGP-XZOQPEGZSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM260745 (US9533989, 56) Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2ccc3CCN(Cc3c2)C(=O)c2cccc(F)c2)n1 Show InChI InChI=1S/C27H30FN7O2/c28-19-5-3-4-17(12-19)26(37)35-11-10-16-8-9-20(13-18(16)15-35)32-25-21(24(30)36)14-31-27(34-25)33-23-7-2-1-6-22(23)29/h3-5,8-9,12-14,22-23H,1-2,6-7,10-11,15,29H2,(H2,30,36)(H2,31,32,33,34)/t22-,23+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.8	n/a	n/a	n/a	n/a	n/a	n/a
Ziarco Pharma Ltd. US Patent					Assay Description The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...				US Patent US9533989 (2017) BindingDB Entry DOI: 10.7270/Q2VQ31M7
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