BDBM260748 US9533989, 59

SMILES: N[C@H]1CCCC[C@H]1Nc1nc(Nc2cccc(c2)-c2ccc(O)cc2)c2c(cc[nH]c2=O)n1

InChI Key: InChIKey=HQTLVBABLYXFCZ-VQTJNVASSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM260748 (US9533989, 59) Show SMILES N[C@H]1CCCC[C@H]1Nc1nc(Nc2cccc(c2)-c2ccc(O)cc2)c2c(cc[nH]c2=O)n1 Show InChI InChI=1S/C25H26N6O2/c26-19-6-1-2-7-20(19)29-25-30-21-12-13-27-24(33)22(21)23(31-25)28-17-5-3-4-16(14-17)15-8-10-18(32)11-9-15/h3-5,8-14,19-20,32H,1-2,6-7,26H2,(H,27,33)(H2,28,29,30,31)/t19-,20+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.3	n/a	n/a	n/a	n/a	n/a	n/a
Ziarco Pharma Ltd. US Patent					Assay Description The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...				US Patent US9533989 (2017) BindingDB Entry DOI: 10.7270/Q2VQ31M7
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