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BDBM260849 US9540323, 36::US9540323, example 36

SMILES: CCC1(CC)CN(c2c1ccc(F)c2O)c1ccccc1NC(=O)Nc1ccc(cc1)C1CCCN1CC(C)C

InChI Key: InChIKey=VWODSRWZKCROBO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260849   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Purinergic receptor P2Y1


(Homo sapiens (Human))		BDBM260849
PNG
(US9540323, 36 | US9540323, example 36)
Show SMILES CCC1(CC)CN(c2c1ccc(F)c2O)c1ccccc1NC(=O)Nc1ccc(cc1)C1CCCN1CC(C)C
Show InChI InChI=1S/C33H41FN4O2/c1-5-33(6-2)21-38(30-25(33)17-18-26(34)31(30)39)29-11-8-7-10-27(29)36-32(40)35-24-15-13-23(14-16-24)28-12-9-19-37(28)20-22(3)4/h7-8,10-11,13-18,22,28,39H,5-6,9,12,19-21H2,1-4H3,(H2,35,36,40)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 5.70 -11.2n/an/an/an/an/a7.425



Bristol-Myers Squibb Company

US Patent


Assay Description
A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...

US Patent US9540323 (2017)


BindingDB Entry DOI: 10.7270/Q289141P
More data for this
Ligand-Target Pair