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BDBM261035 US9540323, 256::US9540323, example 256

SMILES: CC(C)c1noc(n1)-c1c2c(N(CC2(C)C)c2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)c(O)cc1F

InChI Key: InChIKey=SWQMCOAGHPESME-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261035   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2Y purinoceptor 1


(Homo sapiens (Human))		BDBM261035
PNG
(US9540323, 256 | US9540323, example 256)
Show SMILES CC(C)c1noc(n1)-c1c2c(N(CC2(C)C)c2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)c(O)cc1F
Show InChI InChI=1S/C29H27F4N5O4/c1-15(2)25-36-26(42-37-25)22-18(30)13-21(39)24-23(22)28(3,4)14-38(24)20-8-6-5-7-19(20)35-27(40)34-16-9-11-17(12-10-16)41-29(31,32)33/h5-13,15,39H,14H2,1-4H3,(H2,34,35,40)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 6.60 -11.2n/an/an/an/an/a7.425



Bristol-Myers Squibb Company

US Patent


Assay Description
A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...

US Patent US9540323 (2017)


BindingDB Entry DOI: 10.7270/Q289141P
More data for this
Ligand-Target Pair