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BDBM261040 US9540323, 261::US9540323, example 261

SMILES: CC1(C)CN(c2c1c(-c1ccno1)c(F)cc2O)c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=KCLNNIRTPQLVCV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261040   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Purinergic receptor P2Y1


(Homo sapiens (Human))		BDBM261040
PNG
(US9540323, 261 | US9540323, example 261)
Show SMILES CC1(C)CN(c2c1c(-c1ccno1)c(F)cc2O)c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C27H22F4N4O4/c1-26(2)14-35(24-20(36)13-17(28)22(23(24)26)21-11-12-32-39-21)19-6-4-3-5-18(19)34-25(37)33-15-7-9-16(10-8-15)38-27(29,30)31/h3-13,36H,14H2,1-2H3,(H2,33,34,37)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 5.5 -11.3n/an/an/an/an/a7.425



Bristol-Myers Squibb Company

US Patent


Assay Description
A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...

US Patent US9540323 (2017)


BindingDB Entry DOI: 10.7270/Q289141P
More data for this
Ligand-Target Pair