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SMILES: CCOc1c(cc(C#N)c(C)c1-c1cnn(C)c1)C(C)Nc1ncnc(N)c1C(C)=N

InChI Key: InChIKey=DKPDDCVWWZLCGE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261187   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform


(Homo sapiens (Human))		BDBM261187
PNG
(5-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]pyrimidi...)
Show SMILES CCOc1c(cc(C#N)c(C)c1-c1cnn(C)c1)C(C)Nc1ncnc(N)c1C(C)=N
Show InChI InChI=1S/C22H26N8O/c1-6-31-20-17(14(4)29-22-19(13(3)24)21(25)26-11-27-22)7-15(8-23)12(2)18(20)16-9-28-30(5)10-16/h7,9-11,14,24H,6H2,1-5H3,(H3,25,26,27,29)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/a6.725



Incyte Holdings Corporation; Incyte Corporation

US Patent


Assay Description
Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...

US Patent US9707233 (2017)


BindingDB Entry DOI: 10.7270/Q2S46V0R
More data for this
Ligand-Target Pair