null

SMILES: Nc1nc2nccc(-c3ccc(c(c3-c3nnn[nH]3)S(N)(=O)=O)C(F)(F)F)c2[nH]1

InChI Key: InChIKey=MUVOMQQQMNGNCZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM262717 (3-(2-amino-1H-imidazo[4,5-b]pyridin-7-yl)-2-(1H-te...) Show SMILES Nc1nc2nccc(-c3ccc(c(c3-c3nnn[nH]3)S(N)(=O)=O)C(F)(F)F)c2[nH]1 Show InChI InChI=1S/C14H10F3N9O2S/c15-14(16,17)7-2-1-5(6-3-4-20-12-9(6)21-13(18)22-12)8(10(7)29(19,27)28)11-23-25-26-24-11/h1-4H,(H2,19,27,28)(H3,18,20,21,22)(H,23,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.06	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
VIM-1 metallo-beta-lactamase (Klebsiella pneumoniae)	BDBM262717 (3-(2-amino-1H-imidazo[4,5-b]pyridin-7-yl)-2-(1H-te...) Show SMILES Nc1nc2nccc(-c3ccc(c(c3-c3nnn[nH]3)S(N)(=O)=O)C(F)(F)F)c2[nH]1 Show InChI InChI=1S/C14H10F3N9O2S/c15-14(16,17)7-2-1-5(6-3-4-20-12-9(6)21-13(18)22-12)8(10(7)29(19,27)28)11-23-25-26-24-11/h1-4H,(H2,19,27,28)(H3,18,20,21,22)(H,23,24,25,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.490	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM262717 (3-(2-amino-1H-imidazo[4,5-b]pyridin-7-yl)-2-(1H-te...) Show SMILES Nc1nc2nccc(-c3ccc(c(c3-c3nnn[nH]3)S(N)(=O)=O)C(F)(F)F)c2[nH]1 Show InChI InChI=1S/C14H10F3N9O2S/c15-14(16,17)7-2-1-5(6-3-4-20-12-9(6)21-13(18)22-12)8(10(7)29(19,27)28)11-23-25-26-24-11/h1-4H,(H2,19,27,28)(H3,18,20,21,22)(H,23,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	7.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US9708336 (2017) BindingDB Entry DOI: 10.7270/Q2FN186K
					More data for this Ligand-Target Pair