BDBM2633 3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-4-nitro-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::Bisindolylmaleimide deriv. 55

SMILES: Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3cccc([N+]([O-])=O)c23)c2ccccc12

InChI Key: InChIKey=LNSJKQOQRBZRIO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM2633 (3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-4-nitro-1H-...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3cccc([N+]([O-])=O)c23)c2ccccc12 |t:4| Show InChI InChI=1S/C22H16N4O4/c1-24-10-13(12-6-3-4-7-15(12)24)19-20(22(28)23-21(19)27)14-11-25(2)16-8-5-9-17(18(14)16)26(29)30/h3-11H,1-2H3,(H,23,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rattus norvegicus (rat))	BDBM2633 (3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-4-nitro-1H-...) Show SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C)c3cccc([N+]([O-])=O)c23)c2ccccc12 |t:4| Show InChI InChI=1S/C22H16N4O4/c1-24-10-13(12-6-3-4-7-15(12)24)19-20(22(28)23-21(19)27)14-11-25(2)16-8-5-9-17(18(14)16)26(29)30/h3-11H,1-2H3,(H,23,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited					Assay Description The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...				J Med Chem 35: 177-84 (1992) Article DOI: 10.1021/jm00079a024 BindingDB Entry DOI: 10.7270/Q2K64G8V
					More data for this Ligand-Target Pair