BDBM26334 1-{3-[2-(azetidin-1-yl)ethyl]phenyl}-3-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1,3-thiazol-2-yl]urea::thieno[3,2-d]pyrimidine analogue, 29

SMILES: O=C(Nc1ncc(CCNc2ncnc3ccsc23)s1)Nc1cccc(CCN2CCC2)c1

InChI Key: InChIKey=HEUMDSXNTRSQHK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM26334 (1-{3-[2-(azetidin-1-yl)ethyl]phenyl}-3-[5-(2-{thie...) Show SMILES O=C(Nc1ncc(CCNc2ncnc3ccsc23)s1)Nc1cccc(CCN2CCC2)c1 Show InChI InChI=1S/C23H25N7OS2/c31-22(28-17-4-1-3-16(13-17)6-11-30-9-2-10-30)29-23-25-14-18(33-23)5-8-24-21-20-19(7-12-32-20)26-15-27-21/h1,3-4,7,12-15H,2,5-6,8-11H2,(H,24,26,27)(H2,25,28,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals					Assay Description Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...				Bioorg Med Chem Lett 18: 4880-4 (2008) Article DOI: 10.1016/j.bmcl.2008.07.073 BindingDB Entry DOI: 10.7270/Q279430N
					More data for this Ligand-Target Pair
Aurora Kinase A (Aurora-A) (Mus musculus (mouse))	BDBM26334 (1-{3-[2-(azetidin-1-yl)ethyl]phenyl}-3-[5-(2-{thie...) Show SMILES O=C(Nc1ncc(CCNc2ncnc3ccsc23)s1)Nc1cccc(CCN2CCC2)c1 Show InChI InChI=1S/C23H25N7OS2/c31-22(28-17-4-1-3-16(13-17)6-11-30-9-2-10-30)29-23-25-14-18(33-23)5-8-24-21-20-19(7-12-32-20)26-15-27-21/h1,3-4,7,12-15H,2,5-6,8-11H2,(H,24,26,27)(H2,25,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	7.2	21
Sunesis Pharmaceuticals					Assay Description Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...				Bioorg Med Chem Lett 18: 4880-4 (2008) Article DOI: 10.1016/j.bmcl.2008.07.073 BindingDB Entry DOI: 10.7270/Q279430N
					More data for this Ligand-Target Pair