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SMILES: C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccccc1C

InChI Key: InChIKey=ZKALVEIABNRJPU-ZDUSSCGKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 263433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 139 (Homo sapiens (Human))	BDBM263433 ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) Show SMILES C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccccc1C |r| Show InChI InChI=1S/C18H18N4O2/c1-12-7-3-4-8-14(12)13(2)19-17(23)11-22-18(24)15-9-5-6-10-16(15)20-21-22/h3-10,13H,11H2,1-2H3,(H,19,23)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1.15E+3	-7.53	n/a	n/a	n/a	n/a	n/a	7.4	4
Takeda Pharmaceutical Company Limited US Patent					Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...				US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 139 (Homo sapiens (Human))	BDBM263433 ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) Show SMILES C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccccc1C |r| Show InChI InChI=1S/C18H18N4O2/c1-12-7-3-4-8-14(12)13(2)19-17(23)11-22-18(24)15-9-5-6-10-16(15)20-21-22/h3-10,13H,11H2,1-2H3,(H,19,23)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem		1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 139 (Homo sapiens (Human))	BDBM263433 ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) Show SMILES C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccccc1C |r| Show InChI InChI=1S/C18H18N4O2/c1-12-7-3-4-8-14(12)13(2)19-17(23)11-22-18(24)15-9-5-6-10-16(15)20-21-22/h3-10,13H,11H2,1-2H3,(H,19,23)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem		1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 139 (Homo sapiens (Human))	BDBM263433 ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) Show SMILES C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccccc1C |r| Show InChI InChI=1S/C18H18N4O2/c1-12-7-3-4-8-14(12)13(2)19-17(23)11-22-18(24)15-9-5-6-10-16(15)20-21-22/h3-10,13H,11H2,1-2H3,(H,19,23)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	1.15E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...				US Patent US10561662 (2020) BindingDB Entry DOI: 10.7270/Q2Q52S1K
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 139 (Homo sapiens (Human))	BDBM263433 ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) Show SMILES C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccccc1C |r| Show InChI InChI=1S/C18H18N4O2/c1-12-7-3-4-8-14(12)13(2)19-17(23)11-22-18(24)15-9-5-6-10-16(15)20-21-22/h3-10,13H,11H2,1-2H3,(H,19,23)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem		n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair