BDBM263485 (s)?n-(1-(2-fluoro-4-methylphenyl)ethyl)-2-(4-oxobenzo[d][1,2,3]triazin-3 (4h)-yl)acetamide::US10561662, Example 53::US9556130, test 53
SMILES: C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccc(C)cc1F
InChI Key: InChIKey=DVGUHHIULIPPKB-LBPRGKRZSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263485 ((s)?n-(1-(2-fluoro-4-methylphenyl)ethyl)-2-(4-oxob...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 171 | -8.58 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Company Limited US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263485 ((s)?n-(1-(2-fluoro-4-methylphenyl)ethyl)-2-(4-oxob...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.71E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US10561662 (2020) BindingDB Entry DOI: 10.7270/Q2Q52S1K | |||||||||||
More data for this Ligand-Target Pair |