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SMILES: Fc1ccc2[nH]cc(CCCN3CCN(CC3)c3ccc(cc3)-n3ccccc3=O)c2c1

InChI Key: InChIKey=LCGHEWJKAACVME-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 264099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM264099 (1-(4-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazi...) Show SMILES Fc1ccc2[nH]cc(CCCN3CCN(CC3)c3ccc(cc3)-n3ccccc3=O)c2c1 Show InChI InChI=1S/C26H27FN4O/c27-21-6-11-25-24(18-21)20(19-28-25)4-3-12-29-14-16-30(17-15-29)22-7-9-23(10-8-22)31-13-2-1-5-26(31)32/h1-2,5-11,13,18-19,28H,3-4,12,14-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.870	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...				US Patent US9714232 (2017) BindingDB Entry DOI: 10.7270/Q28054N5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM264099 (1-(4-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazi...) Show SMILES Fc1ccc2[nH]cc(CCCN3CCN(CC3)c3ccc(cc3)-n3ccccc3=O)c2c1 Show InChI InChI=1S/C26H27FN4O/c27-21-6-11-25-24(18-21)20(19-28-25)4-3-12-29-14-16-30(17-15-29)22-7-9-23(10-8-22)31-13-2-1-5-26(31)32/h1-2,5-11,13,18-19,28H,3-4,12,14-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	7.4	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...				US Patent US9714232 (2017) BindingDB Entry DOI: 10.7270/Q28054N5
					More data for this Ligand-Target Pair