BindingDB logo
myBDB logout

null

SMILES: COc1ccc(CCC(O)=O)cc1-c1ccc(nc1CN1C(=O)O[C@H](c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C11CC1)C(F)(F)F

InChI Key: InChIKey=KJZCHHURHAFEHN-RUZDIDTESA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264521   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM264521
PNG
(3-{3-[2-({(7R)-7-[3,5- bis(trifluoromethyl)phenyl]...)
Show SMILES COc1ccc(CCC(O)=O)cc1-c1ccc(nc1CN1C(=O)O[C@H](c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C11CC1)C(F)(F)F |r|
Show InChI InChI=1S/C30H23F9N2O5/c1-45-22-5-2-15(3-7-24(42)43)10-20(22)19-4-6-23(30(37,38)39)40-21(19)14-41-26(44)46-25(27(41)8-9-27)16-11-17(28(31,32)33)13-18(12-16)29(34,35)36/h2,4-6,10-13,25H,3,7-9,14H2,1H3,(H,42,43)/t25-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.36E+3n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Transfer assays are performed in a 96-well v-bottom polypropylene plate. For the RTA using recombinant CETP (2% RTA), an assay cocktail is prepared w...

US Patent US9717714 (2017)


BindingDB Entry DOI: 10.7270/Q2TQ63J0
More data for this
Ligand-Target Pair