BDBM264598 US9718760, C155
SMILES: CCCCCCCCN(S(=O)(=O)c1cc(F)c(O)c(F)c1)S(=O)(=O)c1cc(F)c(O)c(F)c1
InChI Key: InChIKey=FOAHHPUOTLUEKB-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PAI-1/uPA (Homo sapiens (Human)) | BDBM264598 (US9718760, C155) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.04E+4 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima... | US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATIII/alphaIIa (Homo sapiens (Human)) | BDBM264598 (US9718760, C155) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.33E+6 | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph... | US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PAI-1/tPA (Homo sapiens (Human)) | BDBM264598 (US9718760, C155) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.48E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph... | US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK | |||||||||||
More data for this Ligand-Target Pair |