BDBM264629 US9718760, C190

SMILES: Oc1ccc(cc1O)S(=O)(=O)Nc1ccc(cc1)-c1cccc(F)c1

InChI Key: InChIKey=DEIBHSFINBLDLJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PAI-1/uPA (Homo sapiens (Human))	BDBM264629 (US9718760, C190) Show SMILES Oc1ccc(cc1O)S(=O)(=O)Nc1ccc(cc1)-c1cccc(F)c1 Show InChI InChI=1S/C18H14FNO4S/c19-14-3-1-2-13(10-14)12-4-6-15(7-5-12)20-25(23,24)16-8-9-17(21)18(22)11-16/h1-11,20-22H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair