BDBM264631 US9718760, C232

SMILES: Oc1ccc(cc1O)S(=O)(=O)NCCCc1ccccc1

InChI Key: InChIKey=UKWORTHCFVNIBP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PAI-1/uPA (Homo sapiens (Human))	BDBM264631 (US9718760, C232) Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCCCc1ccccc1 Show InChI InChI=1S/C15H17NO4S/c17-14-9-8-13(11-15(14)18)21(19,20)16-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,16-18H,4,7,10H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair