null

SMILES: C[C@@H](O)Cc1cc(F)c(c(F)c1)-c1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1

InChI Key: InChIKey=PAGICJYJCMCHII-NIRJSFQDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 265005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM265005 (US9718792, 116) Show SMILES C[C@@H](O)Cc1cc(F)c(c(F)c1)-c1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1 |r,wU:22.24,1.1,wD:24.26,t:21,(-9.61,-4.77,;-8.28,-4,;-8.28,-2.46,;-6.95,-4.77,;-5.61,-4,;-4.28,-4.77,;-2.95,-4,;-1.61,-4.77,;-2.95,-2.46,;-4.28,-1.69,;-4.28,-.15,;-5.61,-2.46,;-1.61,-1.69,;-1.61,-.15,;-.28,.62,;1.06,-.15,;1.06,-1.69,;-.28,-2.46,;-.28,-4,;2.39,.62,;2.87,2.08,;4.41,2.08,;4.88,.62,;6.42,.62,;7.19,1.95,;8.28,3.04,;8.28,.86,;9.61,1.63,;7.51,-.47,;8.28,-1.81,;6.42,3.28,;7.91,3.68,;6.82,4.77,;4.93,3.68,;3.64,-.29,)| Show InChI InChI=1S/C23H25F3N2O6S/c1-12(29)6-13-7-18(25)21(19(26)8-13)16-5-4-14(9-17(16)24)20-10-15(34-28-20)11-23(2,22(30)27-31)35(3,32)33/h4-5,7-9,12,15,29,31H,6,10-11H2,1-3H3,(H,27,30)/t12-,15-,23-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00100	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...				US Patent US9718792 (2017) BindingDB Entry DOI: 10.7270/Q2XG9T4Z
					More data for this Ligand-Target Pair