BDBM266616 US9718790, I-2350

SMILES: CCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccsn3)cc2)n(C[C@H]2CC[C@H](C)CC2)c1=O

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 266616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM266616 (US9718790, I-2350) Show SMILES CCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccsn3)cc2)n(C[C@H]2CC[C@H](C)CC2)c1=O |r,wU:22.23,wD:25.27,(5.96,1.13,;4.62,1.9,;3.29,1.13,;1.96,1.9,;1.96,3.44,;.62,1.13,;.62,-.41,;-.71,-1.18,;-2.04,-.41,;-2.04,1.13,;-3.38,1.9,;-4.71,1.13,;-6.05,1.9,;-6.05,3.44,;-4.8,4.34,;-5.28,5.8,;-6.82,5.8,;-7.29,4.34,;-4.71,-.41,;-3.38,-1.18,;1.96,-1.18,;1.96,-2.72,;3.29,-3.49,;4.62,-2.72,;5.96,-3.49,;5.96,-5.03,;7.29,-5.8,;4.62,-5.8,;3.29,-5.03,;3.29,-.41,;4.62,-1.18,)| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair