BDBM26699 9-butyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2,3-c][1,2]oxazole-3,4-dione::Isoxazoloquinolinedione, 7

SMILES: CCCCn1c2noc(=O)c2c(O)c2cc(F)c(Cl)cc12

InChI Key: InChIKey=UWQLIXURTCXRJT-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM26699 (9-butyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2,...) Show SMILES CCCCn1c2noc(=O)c2c(O)c2cc(F)c(Cl)cc12 Show InChI InChI=1S/C14H12ClFN2O3/c1-2-3-4-18-10-6-8(15)9(16)5-7(10)12(19)11-13(18)17-21-14(11)20/h5-6,19H,2-4H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	15	-10.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...				Bioorg Med Chem Lett 18: 5206-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.079 BindingDB Entry DOI: 10.7270/Q2833QBF
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM26699 (9-butyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2,...) Show SMILES CCCCn1c2noc(=O)c2c(O)c2cc(F)c(Cl)cc12 Show InChI InChI=1S/C14H12ClFN2O3/c1-2-3-4-18-10-6-8(15)9(16)5-7(10)12(19)11-13(18)17-21-14(11)20/h5-6,19H,2-4H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	165	-9.15	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...				Bioorg Med Chem Lett 18: 5206-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.079 BindingDB Entry DOI: 10.7270/Q2833QBF
					More data for this Ligand-Target Pair