BDBM267028 Methyl 4-({[3-(2,3-dihydro-1-benzofuran-5-yl)benzyl]sulfonyl}amino)-2-hydroxybenzoate::US9718809, 122

SMILES: COC(=O)c1ccc(NS(=O)(=O)Cc2cccc(c2)-c2ccc3OCCc3c2)cc1O

InChI Key: InChIKey=ZCTNPSOBORHBEW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) (Homo sapiens (Human))	BDBM267028 (Methyl 4-({[3-(2,3-dihydro-1-benzofuran-5-yl)benzy...) Show SMILES COC(=O)c1ccc(NS(=O)(=O)Cc2cccc(c2)-c2ccc3OCCc3c2)cc1O Show InChI InChI=1S/C23H21NO6S/c1-29-23(26)20-7-6-19(13-21(20)25)24-31(27,28)14-15-3-2-4-16(11-15)17-5-8-22-18(12-17)9-10-30-22/h2-8,11-13,24-25H,9-10,14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair