BDBM267034 Methyl 4-{[(3-chloro-4-fluorophenyl)sulfonyl]amino}-2-hydroxybenzoate::US9718809, 32

SMILES: COC(=O)c1ccc(NS(=O)(=O)c2ccc(F)c(Cl)c2)cc1O

InChI Key: InChIKey=SJVMVYAXRGLLSA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (Homo sapiens (Human))	BDBM267034 (Methyl 4-{[(3-chloro-4-fluorophenyl)sulfonyl]amino...) Show SMILES COC(=O)c1ccc(NS(=O)(=O)c2ccc(F)c(Cl)c2)cc1O Show InChI InChI=1S/C14H11ClFNO5S/c1-22-14(19)10-4-2-8(6-13(10)18)17-23(20,21)9-3-5-12(16)11(15)7-9/h2-7,17-18H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair