BDBM267036 Methyl 4-{[(4-fluoro-1-naphthyl)sulfonyl]amino}-2-hydroxybenzoate::US9718809, 33

SMILES: COC(=O)c1ccc(NS(=O)(=O)c2ccc(F)c3ccccc23)cc1O

InChI Key: InChIKey=UWITXGASQFRWQI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) (Homo sapiens (Human))	BDBM267036 (Methyl 4-{[(4-fluoro-1-naphthyl)sulfonyl]amino}-2-...) Show SMILES COC(=O)c1ccc(NS(=O)(=O)c2ccc(F)c3ccccc23)cc1O Show InChI InChI=1S/C18H14FNO5S/c1-25-18(22)14-7-6-11(10-16(14)21)20-26(23,24)17-9-8-15(19)12-4-2-3-5-13(12)17/h2-10,20-21H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair