BDBM267046 Methyl 4-[(1-benzothien-3-ylsulfonyl)amino]-2-hydroxybenzoate::US9718809, 52

SMILES: COC(=O)c1ccc(NS(=O)(=O)c2csc3ccccc23)cc1O

InChI Key: InChIKey=ACFYMRHLUHALBG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) (Homo sapiens (Human))	BDBM267046 (Methyl 4-[(1-benzothien-3-ylsulfonyl)amino]-2-hydr...) Show SMILES COC(=O)c1ccc(NS(=O)(=O)c2csc3ccccc23)cc1O Show InChI InChI=1S/C16H13NO5S2/c1-22-16(19)11-7-6-10(8-13(11)18)17-24(20,21)15-9-23-14-5-3-2-4-12(14)15/h2-9,17-18H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair