BDBM267089 1-(Methoxymethyl)propyl 4-{[(4,5-dichlorothiophen-2-yl)sulfonyl]amino}-2-hydroxybenzoate::US9718809, 195

SMILES: CCC(COC)OC(=O)c1ccc(NS(=O)(=O)c2cc(Cl)c(Cl)s2)cc1O

InChI Key: InChIKey=TUZSLEYRYGYNLC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (Homo sapiens (Human))	BDBM267089 (1-(Methoxymethyl)propyl 4-{[(4,5-dichlorothiophen-...) Show SMILES CCC(COC)OC(=O)c1ccc(NS(=O)(=O)c2cc(Cl)c(Cl)s2)cc1O Show InChI InChI=1S/C16H17Cl2NO6S2/c1-3-10(8-24-2)25-16(21)11-5-4-9(6-13(11)20)19-27(22,23)14-7-12(17)15(18)26-14/h4-7,10,19-20H,3,8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair