BDBM267092 2-Phenoxyethyl 4-{[(5'-fluoro-2'-hydroxybiphenyl-3-yl)sulfonyl]amino}-2-hydroxybenzoate::US9718809, 203

SMILES: Oc1cc(NS(=O)(=O)c2cccc(c2)-c2cc(F)ccc2O)ccc1C(=O)OCCOc1ccccc1

InChI Key: InChIKey=AASNXEHGRQIULX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) (Homo sapiens (Human))	BDBM267092 (2-Phenoxyethyl 4-{[(5'-fluoro-2'-hydroxybiphenyl-3...) Show SMILES Oc1cc(NS(=O)(=O)c2cccc(c2)-c2cc(F)ccc2O)ccc1C(=O)OCCOc1ccccc1 Show InChI InChI=1S/C27H22FNO7S/c28-19-9-12-25(30)24(16-19)18-5-4-8-22(15-18)37(33,34)29-20-10-11-23(26(31)17-20)27(32)36-14-13-35-21-6-2-1-3-7-21/h1-12,15-17,29-31H,13-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kancera AB US Patent					Assay Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...				US Patent US9718809 (2017) BindingDB Entry DOI: 10.7270/Q28S4RXR
					More data for this Ligand-Target Pair