BDBM2676 3,4-bis(1H-indol-3-yl)pyrrolidine-2,5-dione::Bisindolyl deriv. 6

SMILES: O=C1NC(=O)C(C1c1c[nH]c2ccccc12)c1c[nH]c2ccccc12

InChI Key: InChIKey=QBMMMCZNMCDPBJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM2676 (3,4-bis(1H-indol-3-yl)pyrrolidine-2,5-dione | Bisi...) Show SMILES O=C1NC(=O)C(C1c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C20H15N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,17-18,21-22H,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	30
Laboratoires Glaxo					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Biol Chem 266: 15771-81 (1991) BindingDB Entry DOI: 10.7270/Q2FF3QJ4
					More data for this Ligand-Target Pair