null

SMILES: C1CCC(OC1)n1nccc1-c1nccc2c(cc(nc12)N1CCOCC1)C1=CCNCC1

InChI Key: InChIKey=FEQIJBIKXCHEFP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase ATR (Homo sapiens (Human))	BDBM267985 (2-(morpholin-4-yl)-8-(1H-pyrazol-5-yl)-4-(1,2,3,6-...) Show SMILES C1CCC(OC1)n1nccc1-c1nccc2c(cc(nc12)N1CCOCC1)C1=CCNCC1 |t:32| Show InChI InChI=1S/C25H30N6O2/c1-2-14-33-23(3-1)31-21(7-11-28-31)25-24-19(6-10-27-25)20(18-4-8-26-9-5-18)17-22(29-24)30-12-15-32-16-13-30/h4,6-7,10-11,17,23,26H,1-3,5,8-9,12-16H2	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	117	n/a	n/a	n/a	n/a	7.0	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo...				US Patent US9549932 (2017) BindingDB Entry DOI: 10.7270/Q27S7QSC
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase ATR (Homo sapiens (Human))	BDBM267985 (2-(morpholin-4-yl)-8-(1H-pyrazol-5-yl)-4-(1,2,3,6-...) Show SMILES C1CCC(OC1)n1nccc1-c1nccc2c(cc(nc12)N1CCOCC1)C1=CCNCC1 |t:32| Show InChI InChI=1S/C25H30N6O2/c1-2-14-33-23(3-1)31-21(7-11-28-31)25-24-19(6-10-27-25)20(18-4-8-26-9-5-18)17-22(29-24)30-12-15-32-16-13-30/h4,6-7,10-11,17,23,26H,1-3,5,8-9,12-16H2	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	185	n/a	n/a	n/a	n/a	7.0	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo...				US Patent US9549932 (2017) BindingDB Entry DOI: 10.7270/Q27S7QSC
					More data for this Ligand-Target Pair