BDBM26879 2-aminobenzimidazole with trans-stilbene, 8v::N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoylethyl)-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene]-5-[(E)-2-(1H-pyrazol-4-yl)ethenyl]thiophene-2-carboxamide

SMILES: CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(C=Cc4cn[nH]c4)s3)nc2c1

InChI Key: InChIKey=CQYAVXIHIFJOCO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26879   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM26879 (2-aminobenzimidazole with trans-stilbene, 8v | N-[...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(C=Cc4cn[nH]c4)s3)nc2c1 |w:28.28| Show InChI InChI=1S/C28H25N7O3S/c1-34(27(38)19-5-3-2-4-6-19)20-8-11-23-22(15-20)32-28(35(23)14-13-25(29)36)33-26(37)24-12-10-21(39-24)9-7-18-16-30-31-17-18/h2-12,15-17H,13-14H2,1H3,(H2,29,36)(H,30,31)(H,32,33,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.0	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 18: 6218-21 (2008) Article DOI: 10.1016/j.bmcl.2008.09.098 BindingDB Entry DOI: 10.7270/Q23B5XFW
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM26879 (2-aminobenzimidazole with trans-stilbene, 8v | N-[...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(C=Cc4cn[nH]c4)s3)nc2c1 |w:28.28| Show InChI InChI=1S/C28H25N7O3S/c1-34(27(38)19-5-3-2-4-6-19)20-8-11-23-22(15-20)32-28(35(23)14-13-25(29)36)33-26(37)24-12-10-21(39-24)9-7-18-16-30-31-17-18/h2-12,15-17H,13-14H2,1H3,(H2,29,36)(H,30,31)(H,32,33,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 18: 6218-21 (2008) Article DOI: 10.1016/j.bmcl.2008.09.098 BindingDB Entry DOI: 10.7270/Q23B5XFW
					More data for this Ligand-Target Pair