BDBM26880 2-aminobenzimidazole with trans-stilbene, 8w::5-[(E)-2-(6-aminopyridin-2-yl)ethenyl]-N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoylethyl)-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene]thiophene-2-carboxamide

SMILES: CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(C=Cc4cccc(N)n4)s3)nc2c1

InChI Key: InChIKey=OSXNSJYAHZGKMH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM26880 (2-aminobenzimidazole with trans-stilbene, 8w | 5-[...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(C=Cc4cccc(N)n4)s3)nc2c1 |w:28.28| Show InChI InChI=1S/C30H27N7O3S/c1-36(29(40)19-6-3-2-4-7-19)21-11-14-24-23(18-21)34-30(37(24)17-16-27(32)38)35-28(39)25-15-13-22(41-25)12-10-20-8-5-9-26(31)33-20/h2-15,18H,16-17H2,1H3,(H2,31,33)(H2,32,38)(H,34,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.0	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 18: 6218-21 (2008) Article DOI: 10.1016/j.bmcl.2008.09.098 BindingDB Entry DOI: 10.7270/Q23B5XFW
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM26880 (2-aminobenzimidazole with trans-stilbene, 8w | 5-[...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(C=Cc4cccc(N)n4)s3)nc2c1 |w:28.28| Show InChI InChI=1S/C30H27N7O3S/c1-36(29(40)19-6-3-2-4-7-19)21-11-14-24-23(18-21)34-30(37(24)17-16-27(32)38)35-28(39)25-15-13-22(41-25)12-10-20-8-5-9-26(31)33-20/h2-15,18H,16-17H2,1H3,(H2,31,33)(H2,32,38)(H,34,35,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 18: 6218-21 (2008) Article DOI: 10.1016/j.bmcl.2008.09.098 BindingDB Entry DOI: 10.7270/Q23B5XFW
					More data for this Ligand-Target Pair