BDBM26886 2-aminobenzimidazole with trans-stilbene, 9b::N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoylethyl)-2,3-dihydro-1H-1,3-benzodiazol-2-ylidene]-5-[(1E)-1-(pyridin-3-yl)prop-1-en-2-yl]thiophene-2-carboxamide

SMILES: CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(s3)C(C)=Cc3cccnc3)nc2c1

InChI Key: InChIKey=RMPKLJSKGHAHCY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM26886 (2-aminobenzimidazole with trans-stilbene, 9b | N-[...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(s3)C(C)=Cc3cccnc3)nc2c1 |w:31.33| Show InChI InChI=1S/C31H28N6O3S/c1-20(17-21-7-6-15-33-19-21)26-12-13-27(41-26)29(39)35-31-34-24-18-23(10-11-25(24)37(31)16-14-28(32)38)36(2)30(40)22-8-4-3-5-9-22/h3-13,15,17-19H,14,16H2,1-2H3,(H2,32,38)(H,34,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	7.0	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 18: 6218-21 (2008) Article DOI: 10.1016/j.bmcl.2008.09.098 BindingDB Entry DOI: 10.7270/Q23B5XFW
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM26886 (2-aminobenzimidazole with trans-stilbene, 9b | N-[...) Show SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccc(s3)C(C)=Cc3cccnc3)nc2c1 |w:31.33| Show InChI InChI=1S/C31H28N6O3S/c1-20(17-21-7-6-15-33-19-21)26-12-13-27(41-26)29(39)35-31-34-24-18-23(10-11-25(24)37(31)16-14-28(32)38)36(2)30(40)22-8-4-3-5-9-22/h3-13,15,17-19H,14,16H2,1-2H3,(H2,32,38)(H,34,35,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...				Bioorg Med Chem Lett 18: 6218-21 (2008) Article DOI: 10.1016/j.bmcl.2008.09.098 BindingDB Entry DOI: 10.7270/Q23B5XFW
					More data for this Ligand-Target Pair