null

SMILES: Clc1ccccc1C(N1CCC2(CC1)N(CN(CCN1CCCC1)C2=O)c1ccccc1)c1ccccc1Cl

InChI Key: InChIKey=NJDAIEKCJUPYPX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM26916 (8-[bis(2-chlorophenyl)methyl]-1-phenyl-3-[2-(pyrro...) Show SMILES Clc1ccccc1C(N1CCC2(CC1)N(CN(CCN1CCCC1)C2=O)c1ccccc1)c1ccccc1Cl Show InChI InChI=1S/C32H36Cl2N4O/c33-28-14-6-4-12-26(28)30(27-13-5-7-15-29(27)34)36-20-16-32(17-21-36)31(39)37(23-22-35-18-8-9-19-35)24-38(32)25-10-2-1-3-11-25/h1-7,10-15,30H,8-9,16-24H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	2.25	-11.7	n/a	n/a	n/a	n/a	n/a	7.4	22
Schering-Plough Research Institute					Assay Description IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...				Bioorg Med Chem Lett 19: 1164-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.092 BindingDB Entry DOI: 10.7270/Q2TT4P95
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM26916 (8-[bis(2-chlorophenyl)methyl]-1-phenyl-3-[2-(pyrro...) Show SMILES Clc1ccccc1C(N1CCC2(CC1)N(CN(CCN1CCCC1)C2=O)c1ccccc1)c1ccccc1Cl Show InChI InChI=1S/C32H36Cl2N4O/c33-28-14-6-4-12-26(28)30(27-13-5-7-15-29(27)34)36-20-16-32(17-21-36)31(39)37(23-22-35-18-8-9-19-35)24-38(32)25-10-2-1-3-11-25/h1-7,10-15,30H,8-9,16-24H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	254	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute					Assay Description IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...				Bioorg Med Chem Lett 19: 1164-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.092 BindingDB Entry DOI: 10.7270/Q2TT4P95
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM26916 (8-[bis(2-chlorophenyl)methyl]-1-phenyl-3-[2-(pyrro...) Show SMILES Clc1ccccc1C(N1CCC2(CC1)N(CN(CCN1CCCC1)C2=O)c1ccccc1)c1ccccc1Cl Show InChI InChI=1S/C32H36Cl2N4O/c33-28-14-6-4-12-26(28)30(27-13-5-7-15-29(27)34)36-20-16-32(17-21-36)31(39)37(23-22-35-18-8-9-19-35)24-38(32)25-10-2-1-3-11-25/h1-7,10-15,30H,8-9,16-24H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	436	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute					Assay Description IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...				Bioorg Med Chem Lett 19: 1164-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.092 BindingDB Entry DOI: 10.7270/Q2TT4P95
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM26916 (8-[bis(2-chlorophenyl)methyl]-1-phenyl-3-[2-(pyrro...) Show SMILES Clc1ccccc1C(N1CCC2(CC1)N(CN(CCN1CCCC1)C2=O)c1ccccc1)c1ccccc1Cl Show InChI InChI=1S/C32H36Cl2N4O/c33-28-14-6-4-12-26(28)30(27-13-5-7-15-29(27)34)36-20-16-32(17-21-36)31(39)37(23-22-35-18-8-9-19-35)24-38(32)25-10-2-1-3-11-25/h1-7,10-15,30H,8-9,16-24H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	906	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute					Assay Description IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...				Bioorg Med Chem Lett 19: 1164-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.092 BindingDB Entry DOI: 10.7270/Q2TT4P95
					More data for this Ligand-Target Pair