BDBM269452 (E)-2-(2- isopropylphenyl)-3-(4- (2-(5-propyl-4H-1,2,4- triazol-3- yl)vinyl)phenoxy)benzo [b]thiophen-6-ol::US10058534, 107

SMILES: CCCc1nnc(\C=C\c2ccc(Oc3c(sc4cc(O)ccc34)-c3ccccc3C(C)C)cc2)[nH]1

InChI Key: InChIKey=JBZGHUPMHCIGKX-SFQUDFHCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM269452 ((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-propyl-4H-1...) Show SMILES CCCc1nnc(\C=C\c2ccc(Oc3c(sc4cc(O)ccc34)-c3ccccc3C(C)C)cc2)[nH]1 Show InChI InChI=1S/C30H29N3O2S/c1-4-7-27-31-28(33-32-27)17-12-20-10-14-22(15-11-20)35-29-25-16-13-21(34)18-26(25)36-30(29)24-9-6-5-8-23(24)19(2)3/h5-6,8-19,34H,4,7H2,1-3H3,(H,31,32,33)/b17-12+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...				US Patent US10058534 (2018) BindingDB Entry DOI: 10.7270/Q2M32XSG
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM269452 ((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-propyl-4H-1...) Show SMILES CCCc1nnc(\C=C\c2ccc(Oc3c(sc4cc(O)ccc34)-c3ccccc3C(C)C)cc2)[nH]1 Show InChI InChI=1S/C30H29N3O2S/c1-4-7-27-31-28(33-32-27)17-12-20-10-14-22(15-11-20)35-29-25-16-13-21(34)18-26(25)36-30(29)24-9-6-5-8-23(24)19(2)3/h5-6,8-19,34H,4,7H2,1-3H3,(H,31,32,33)/b17-12+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	66	n/a	n/a	n/a	n/a	5.1	37
Novartis AG US Patent					Assay Description The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...				US Patent US10058534 (2018) BindingDB Entry DOI: 10.7270/Q2M32XSG
					More data for this Ligand-Target Pair