BDBM26966 4-aminoquinazoline derivative, 7i::N-(2-aminoethyl)-2-[(E)-2-(4-chlorophenyl)ethenyl]-6-methylquinazolin-4-amine

SMILES: Cc1ccc2nc(\C=C\c3ccc(Cl)cc3)nc(NCCN)c2c1

InChI Key: InChIKey=HVSGNYDJYBCMBH-WEVVVXLNSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM26966 (4-aminoquinazoline derivative, 7i | N-(2-aminoethy...) Show SMILES Cc1ccc2nc(\C=C\c3ccc(Cl)cc3)nc(NCCN)c2c1 Show InChI InChI=1S/C19H19ClN4/c1-13-2-8-17-16(12-13)19(22-11-10-21)24-18(23-17)9-5-14-3-6-15(20)7-4-14/h2-9,12H,10-11,21H2,1H3,(H,22,23,24)/b9-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Shinyaku Co.					Assay Description Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...				Bioorg Med Chem 17: 119-32 (2009) Article DOI: 10.1016/j.bmc.2008.11.012 BindingDB Entry DOI: 10.7270/Q2Q52MX5
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM26966 (4-aminoquinazoline derivative, 7i | N-(2-aminoethy...) Show SMILES Cc1ccc2nc(\C=C\c3ccc(Cl)cc3)nc(NCCN)c2c1 Show InChI InChI=1S/C19H19ClN4/c1-13-2-8-17-16(12-13)19(22-11-10-21)24-18(23-17)9-5-14-3-6-15(20)7-4-14/h2-9,12H,10-11,21H2,1H3,(H,22,23,24)/b9-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	972	-8.20	n/a	n/a	n/a	n/a	n/a	7.8	25
Nippon Shinyaku Co.					Assay Description Competitive binding displacement analysis was performed with membranes prepared from CHO-K1 cells stably expressing receptors. After incubation, samp...				Bioorg Med Chem 17: 119-32 (2009) Article DOI: 10.1016/j.bmc.2008.11.012 BindingDB Entry DOI: 10.7270/Q2Q52MX5
					More data for this Ligand-Target Pair