BDBM270912 4-(azetidin-1-yl)-7-(benzenesulfonyl)-5H-pyrrolo[3,2-d]pyrimidin-6-amine::US10059713, Example 30

SMILES: Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCC1

InChI Key: InChIKey=SIBTYGKBRHWZOC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 270912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270912 (4-(azetidin-1-yl)-7-(benzenesulfonyl)-5H-pyrrolo[3...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCC1 Show InChI InChI=1S/C15H15N5O2S/c16-14-13(23(21,22)10-5-2-1-3-6-10)11-12(19-14)15(18-9-17-11)20-7-4-8-20/h1-3,5-6,9,19H,4,7-8,16H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.53E+3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair