BDBM270930 4-(azepan-1-yl)-7-(benzenesulfonyl)-5H-pyrrolo[3,2-d]pyrimidin-6-amine::US10059713, Example 48

SMILES: Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCCCCC1

InChI Key: InChIKey=IYFCPFLUMCGQRH-UHFFFAOYSA-N

Data: 1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 270930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270930 (4-(azepan-1-yl)-7-(benzenesulfonyl)-5H-pyrrolo[3,2...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCCCCC1 Show InChI InChI=1S/C18H21N5O2S/c19-17-16(26(24,25)13-8-4-3-5-9-13)14-15(22-17)18(21-12-20-14)23-10-6-1-2-7-11-23/h3-5,8-9,12,22H,1-2,6-7,10-11,19H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	209	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair