BDBM270940 7-(benzenesulfonyl)-4-(4-methylpiperidin-1-yl)-5H-pyrrolo[3,2-d]pyrimidin-6-amine::US10059713, Example 59

SMILES: CC1CCN(CC1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=MJXOTTIANSHING-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 270940   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270940 (7-(benzenesulfonyl)-4-(4-methylpiperidin-1-yl)-5H-...) Show SMILES CC1CCN(CC1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H21N5O2S/c1-12-7-9-23(10-8-12)18-15-14(20-11-21-18)16(17(19)22-15)26(24,25)13-5-3-2-4-6-13/h2-6,11-12,22H,7-10,19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair