BDBM271122 4-(2,2-dimethylmorpholin-4-yl)-7-(2-fluoro-4-methoxybenzenesulfonyl)-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-6-amine::US10059713, Example 241
SMILES: COc1ccc(c(F)c1)S(=O)(=O)c1c(N)[nH]c2c(nc(C)nc12)N1CCOC(C)(C)C1
InChI Key: InChIKey=HLZDHCWNADLKPD-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Free fatty acid receptor 2 (Homo sapiens (Human)) | BDBM271122 (4-(2,2-dimethylmorpholin-4-yl)-7-(2-fluoro-4-metho...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 51 | n/a | n/a | n/a | n/a |
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent | Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in... | US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X | |||||||||||
More data for this Ligand-Target Pair |