BDBM271280 US10059720, Example 95::US10975091, Example 95

SMILES: CC(C)C[C@H](N)[C@](O)(Cc1cc(OCCc2ccsc2)ccn1)C(O)=O

InChI Key: InChIKey=GXDKHUZXXWSXQZ-PKOBYXMFSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 271280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucyl-cystinyl aminopeptidase (Rattus norvegicus)	BDBM271280 (US10059720, Example 95 | US10975091, Example 95) Show SMILES CC(C)C[C@H](N)[C@](O)(Cc1cc(OCCc2ccsc2)ccn1)C(O)=O |r| Show InChI InChI=1S/C19H26N2O4S/c1-13(2)9-17(20)19(24,18(22)23)11-15-10-16(3-6-21-15)25-7-4-14-5-8-26-12-14/h3,5-6,8,10,12-13,17,24H,4,7,9,11,20H2,1-2H3,(H,22,23)/t17-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent					Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m...				US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5
					More data for this Ligand-Target Pair
Aminopeptidase (P-LAP) (Homo sapiens (Human))	BDBM271280 (US10059720, Example 95 | US10975091, Example 95) Show SMILES CC(C)C[C@H](N)[C@](O)(Cc1cc(OCCc2ccsc2)ccn1)C(O)=O |r| Show InChI InChI=1S/C19H26N2O4S/c1-13(2)9-17(20)19(24,18(22)23)11-15-10-16(3-6-21-15)25-7-4-14-5-8-26-12-14/h3,5-6,8,10,12-13,17,24H,4,7,9,11,20H2,1-2H3,(H,22,23)/t17-,19+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent					Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...				US Patent US10975091 (2021)
					More data for this Ligand-Target Pair
Cystinyl aminopeptidase (Rattus norvegicus)	BDBM271280 (US10059720, Example 95 | US10975091, Example 95) Show SMILES CC(C)C[C@H](N)[C@](O)(Cc1cc(OCCc2ccsc2)ccn1)C(O)=O |r| Show InChI InChI=1S/C19H26N2O4S/c1-13(2)9-17(20)19(24,18(22)23)11-15-10-16(3-6-21-15)25-7-4-14-5-8-26-12-14/h3,5-6,8,10,12-13,17,24H,4,7,9,11,20H2,1-2H3,(H,22,23)/t17-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent					Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP....				US Patent US10975091 (2021)
					More data for this Ligand-Target Pair
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human))	BDBM271280 (US10059720, Example 95 | US10975091, Example 95) Show SMILES CC(C)C[C@H](N)[C@](O)(Cc1cc(OCCc2ccsc2)ccn1)C(O)=O |r| Show InChI InChI=1S/C19H26N2O4S/c1-13(2)9-17(20)19(24,18(22)23)11-15-10-16(3-6-21-15)25-7-4-14-5-8-26-12-14/h3,5-6,8,10,12-13,17,24H,4,7,9,11,20H2,1-2H3,(H,22,23)/t17-,19+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent					Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...				US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5
					More data for this Ligand-Target Pair