BDBM271306 US10059720, Example 121::US10975091, Example 121

SMILES: CC(C)C[C@H](N)[C@](O)(Cc1cc(SC2CCCCCC2)ccn1)C(O)=O

InChI Key: InChIKey=WVBIVWXUSOUBMN-AZUAARDMSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 271306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucyl-cystinyl aminopeptidase (Rattus norvegicus)	BDBM271306 (US10059720, Example 121 | US10975091, Example 121) Show SMILES CC(C)C[C@H](N)[C@](O)(Cc1cc(SC2CCCCCC2)ccn1)C(O)=O |r| Show InChI InChI=1S/C20H32N2O3S/c1-14(2)11-18(21)20(25,19(23)24)13-15-12-17(9-10-22-15)26-16-7-5-3-4-6-8-16/h9-10,12,14,16,18,25H,3-8,11,13,21H2,1-2H3,(H,23,24)/t18-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent					Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m...				US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5
					More data for this Ligand-Target Pair
Aminopeptidase (P-LAP) (Homo sapiens (Human))	BDBM271306 (US10059720, Example 121 | US10975091, Example 121) Show SMILES CC(C)C[C@H](N)[C@](O)(Cc1cc(SC2CCCCCC2)ccn1)C(O)=O |r| Show InChI InChI=1S/C20H32N2O3S/c1-14(2)11-18(21)20(25,19(23)24)13-15-12-17(9-10-22-15)26-16-7-5-3-4-6-8-16/h9-10,12,14,16,18,25H,3-8,11,13,21H2,1-2H3,(H,23,24)/t18-,20+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent					Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...				US Patent US10975091 (2021)
					More data for this Ligand-Target Pair
Cystinyl aminopeptidase (Rattus norvegicus)	BDBM271306 (US10059720, Example 121 | US10975091, Example 121) Show SMILES CC(C)C[C@H](N)[C@](O)(Cc1cc(SC2CCCCCC2)ccn1)C(O)=O |r| Show InChI InChI=1S/C20H32N2O3S/c1-14(2)11-18(21)20(25,19(23)24)13-15-12-17(9-10-22-15)26-16-7-5-3-4-6-8-16/h9-10,12,14,16,18,25H,3-8,11,13,21H2,1-2H3,(H,23,24)/t18-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent					Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP....				US Patent US10975091 (2021)
					More data for this Ligand-Target Pair
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human))	BDBM271306 (US10059720, Example 121 | US10975091, Example 121) Show SMILES CC(C)C[C@H](N)[C@](O)(Cc1cc(SC2CCCCCC2)ccn1)C(O)=O |r| Show InChI InChI=1S/C20H32N2O3S/c1-14(2)11-18(21)20(25,19(23)24)13-15-12-17(9-10-22-15)26-16-7-5-3-4-6-8-16/h9-10,12,14,16,18,25H,3-8,11,13,21H2,1-2H3,(H,23,24)/t18-,20+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent					Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...				US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5
					More data for this Ligand-Target Pair