BDBM272083 (S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- (pyrazin-2-yl)-1,4,5,6- tetrahydrocyclopenta[c]pyrazole-5-carboxamide::US10065948, 19::US10457675, Example 19

SMILES: Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1cnccn1)C(=O)NO

InChI Key: InChIKey=VCQDHQZHPNUNHZ-SFHVURJKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272083 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- (pyra...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1cnccn1)C(=O)NO |r| Show InChI InChI=1S/C18H16FN5O2/c1-11-13(3-2-4-14(11)19)18(17(25)23-26)7-12-9-22-24(15(12)8-18)16-10-20-5-6-21-16/h2-6,9-10,26H,7-8H2,1H3,(H,23,25)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272083 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- (pyra...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1cnccn1)C(=O)NO |r| Show InChI InChI=1S/C18H16FN5O2/c1-11-13(3-2-4-14(11)19)18(17(25)23-26)7-12-9-22-24(15(12)8-18)16-10-20-5-6-21-16/h2-6,9-10,26H,7-8H2,1H3,(H,23,25)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair