BDBM272187 US10065950, Example 152::US10065950, Example 28

SMILES: CC(C)N1CC(C)(C(=O)N(C)C)n2cc(-c3ncc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c2C1=O

InChI Key: InChIKey=JVPCCVFGISDYRW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
inhibitory activity (Human immunodeficiency virus type 1 group M subtyp...)	BDBM272187 (US10065950, Example 152 | US10065950, Example 28) Show SMILES CC(C)N1CC(C)(C(=O)N(C)C)n2cc(-c3ncc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c2C1=O Show InChI InChI=1S/C25H26F2N4O4S/c1-13(2)30-12-25(3,24(35)29(4)5)31-11-17(20(32)21(33)19(31)23(30)34)22-28-10-16(36-22)8-14-6-7-15(26)9-18(14)27/h6-7,9-11,13,33H,8,12H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	25
Japan Tobacco Inc. US Patent					Assay Description The donor DNA was diluted with TE buffer to 20 nM, of which 50 μL was added to each well of streptavidin-coated black plate (manufactured by PIA...				US Patent US10065950 (2018) BindingDB Entry DOI: 10.7270/Q2RN39V2
					More data for this Ligand-Target Pair
inhibitory activity (Human immunodeficiency virus type 1 group M subtyp...)	BDBM272187 (US10065950, Example 152 | US10065950, Example 28) Show SMILES CC(C)N1CC(C)(C(=O)N(C)C)n2cc(-c3ncc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c2C1=O Show InChI InChI=1S/C25H26F2N4O4S/c1-13(2)30-12-25(3,24(35)29(4)5)31-11-17(20(32)21(33)19(31)23(30)34)22-28-10-16(36-22)8-14-6-7-15(26)9-18(14)27/h6-7,9-11,13,33H,8,12H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	25
Japan Tobacco Inc. US Patent					Assay Description The donor DNA was diluted with TE buffer to 20 nM, of which 50 μL was added to each well of streptavidin-coated black plate (manufactured by PIA...				US Patent US10065950 (2018) BindingDB Entry DOI: 10.7270/Q2RN39V2
					More data for this Ligand-Target Pair