BDBM27232 ARC-1056, 5::[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl N-(5-carbamoylpentyl)carbamate

SMILES: NC(=O)CCCCCNC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key: InChIKey=YKQSSTUVJDMJEJ-RVXWVPLUSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-Dependent Protein Kinase (PKA) (Mus musculus (mouse))	BDBM27232 (ARC-1056, 5 | [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9...) Show SMILES NC(=O)CCCCCNC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C17H25N7O6/c18-10(25)4-2-1-3-5-20-17(28)29-6-9-12(26)13(27)16(30-9)24-8-23-11-14(19)21-7-22-15(11)24/h7-9,12-13,16,26-27H,1-6H2,(H2,18,25)(H,20,28)(H2,19,21,22)/t9-,12-,13-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.21E+4	n/a	n/a	n/a	7.5	30
Institute of Chemistry in Estonia					Assay Description The assay is based on the kinase-bound labeled fluorescent probe can be displaced by competitive inhibitors, which can be registered by measurement o...				J Med Chem 52: 308-21 (2009) Article DOI: 10.1021/jm800797n BindingDB Entry DOI: 10.7270/Q2RX99FQ
					More data for this Ligand-Target Pair